ea0032p973 | Steroid metabolism and action | ECE2013
Bang Anne Kirstine
, Jorgensen Niels
, Rajpert-De Meyts Ewa
, Juul Anders
Introduction: The UGT2B17 gene encodes a glucuronidase which is important for the urinary excretion of testosterone. Recent studies have shown that a common deletion polymorphism in UGT2B17 is strongly associated with significant lower levels of excreted urinary testosterone in men. The objective of this study was to investigate the association of the UGT2B17 gene polymorphism and the dosages of testosterone substitution in male patients with frank hypogonadism.<p class="a...